Embarkation day. MSC Opera sails at 6:00 PM.

MSC Opera
September 25, 2026
10-Night Western Mediterranean aboard MSC Opera · Departing September 25, 2026 from the Port of Lisbon, Portugal.
MSC Opera September 25, 2026 Cruise Overview
MSC Opera leaves Lisbon, Portugal on Friday, September 25, 2026 at 6:00 PM and returns Monday, October 5 at 9:00 AM: 10 nights with 7 ports of call (Alicante, Mahon, Olbia, Genoa Portofino Italy, Marseille, Malaga and Cadiz) and 2 days at sea. It is the only upcoming departure of this itinerary on MSC Opera. September averages 85°F highs and 58°F lows across the ports on this route.
The itinerary safety score for this sailing is 7.4 out of 10, averaged across 8 ports. Inside cabins rose $47 on Sep 24.
MSC Opera September 25, 2026 Roll Call
MSC Opera September 25, 2026 Price & Tracking
The graph below tracks historic price of the MSC Opera cruise ship departing September 25, 2026. The most recent price for this sailing starts at $1,348 ($135 per night) for an Inside Cabin. Compared to the average price of $1,432 ($144 per night), this represents a recent decrease of 6%.
MSC Opera cruise departing September 25, 2026 — 10-night itinerary. Current Inside Cabin price: $1,348 ($135 per night). Average price: $1,432.
Prices change often and may differ at checkout. Click to see the latest available price.
Get an email notification when the price of the MSC Opera – September 25, 2026 drops below $1,348 for an inside cabin.
Gangwaze earns a commission when you book through our partner links at no extra cost to you. Prices shown are sourced from third-party sellers and may differ at checkout.
10 Night Western Mediterranean (Lisbon Roundtrip) Cruise Map
10 Night Western Mediterranean (Lisbon Roundtrip) Port List
At sea
Day at sea aboard the Opera — explore the ship's signature dining, entertainment, and onboard activities.
At sea
Day at sea aboard the Opera.
10 Night Western Mediterranean (Lisbon Roundtrip) Weather Forecast
Most Popular Lisbon Shore Excursions
Independent shore excursions in every port on this MSC Opera itinerary, booked directly with the operator who runs them. We flag the ones that guarantee you're back on board before the gangway lifts.
True 4Hour Private Tuk Tuk Tour: Discover Lisbon with a Local!
Private Lisbon Sightseeing Tuk-Tuk Tour: Alfama, Belém & More
Small Group Tour to Sintra, Pena Palace, Cabo Roca and Cascais
Lisbon Highlights: Private Tuk Tuk Tour Adventure Sightseeing
Small group Sintra, Pena Palace, Regaleira, Cabo Roca, Cascais
Welcome Tour to Lisbon in Private Eco Tuk Tuk with a Local
Lisbon E-Bike Tour Commerce Square, Mouraria and Alfama
Sintra Full Day Private Tour: Including Pena Palace + Regaleira
These are the eight most reviewed. Lisbon has plenty more — browse the full catalogue and book direct with the operator.
SEE ALL LISBON EXCURSIONSPricing and availability are provided by the operator. Booking happens on their own site — MSC Opera sails September 25, 2026, and Gangwaze earns a commission at no extra cost to you.
Itinerary Safety Score
Based on comprehensive research of cruise port safety information, including recent crime reports, travel advisories, Global Peace Index rankings, and specific port security concerns, we've created a "safety score" for each cruise port stop. The overall rating below represents a combined score for your specific cruise itinerary.
Scores combine recent crime reports, government travel advisories, Global Peace Index rankings, and port-specific security incidents. Refreshed monthly.
Travelers in Lisbon should stay vigilant in crowded areas and on public transport to avoid petty theft and keep belongings secure.
Travelers in Alicante should stay vigilant against petty theft, especially in crowded areas, while securing their belongings.
Mahon is a safe cruise destination with low crime rates, though travelers should stay vigilant against pickpocketing in crowded areas.
Olbia is generally safe for travelers, but vigilance against petty theft and pickpocketing is advised in crowded areas.
Genoa and Portofino are generally safe for cruise travelers, but vigilance against petty crime like pickpocketing is advised.
Travelers in Marseille should stay vigilant in certain neighborhoods due to higher crime rates and secure their belongings in crowded areas.
Travelers in Malaga should remain vigilant against petty theft and pickpocketing, especially in crowded areas and popular attractions.
Travelers should stay vigilant against petty theft in crowded areas while enjoying the safe and welcoming atmosphere of Cadiz.
MSC Opera Ship Overview
The MSC Opera has a construction date of 2004 and a total size of 65,591 gross tons. The ship measures 902 feet in length. MSC Opera is included in MSC's Lirica class. At full capacity, the Opera holds 2,679 passengers. That includes 1,951 cruise vacationers and 728 staff members. The Opera total number of staterooms is 1,068.
More MSC Opera cruises
Hop to the previous or next sailing on this ship, or browse the full schedule.
















