

The April 25, 2026 cruise on the Serenade of the Seas departs from Colon, Panama. On this 1 Night Southern Caribbean (Colon To Cartagena) sailing, the ship will visit a total of 2 cruise port destinations, including its departure port. The Serenade of the Seas sets sail on Saturday, Apr 25th and returns on Sunday, Apr 26th.
The graph below tracks historic price of the Serenade of the Seas cruise ship departing April 25, 2026. The most recent price for this sailing starts at $124 ($124 per night) for an Inside Cabin. Compared to the average price of $158 ($159 per night), this represents a recent decrease of 22%.
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Serenade of the Seas - April 25, 2026 - 1 Nights
| Day | Date | Port |
|---|---|---|
| 1 | Apr 25th | Colon, Panama |
| 2 | Apr 19th | Cartagena, Colombia |
The Serenade of the Seas sails on April 25, 2026 for a 1 Night Southern Caribbean (Colon To Cartagena). The ship will depart the port of Colon, Panama at 4:00 PM and will return to the port of Cartagena, Colombia on Apr 26th at 9:00 AM. During the 2-day journey, the Serenade of the Seas will visit 1 additional port and will spend 0 days at sea.

The Serenade of the Seas has a construction date of 2003 and a total size of 90,090 gross tons. The ship measures 962 feet (293 meters) in length. Serenade of the Seas is included in Royal Caribbean’s Radiance Class. At full capacity, the Serenade of the Seas holds 3,027 passengers. That includes 2,143 cruise vacationers and 884 staff members. The Serenade of the Seas total number of staterooms is 1,073.
To see how this compares, click through to see Serenade of the Seas age and stats vs all Royal Caribbean ships. There you’ll find graphs showing length, capacity, tonnage and more for this ship vs all in the fleet.
To check out the ship from top to bottom, click here for Serenade of the Seas Deck Plans.
Colón, Panama, offers docking at Colón Port. Travelers explore Gatun Locks and Fort San Lorenzo. Excursions include Emberá village tours. Local markets sell sancocho. The peak season, December to April, brings dry weather for coastal tours. Photography captures canal locks and Caribbean vistas. Dining onboard includes arroz con pollo, a Panamanian favorite. Souvenirs, like molas, are sold in ship shops. Briefings cover Kuna history. Light clothing and sun protection suit the tropical climate, while sturdy shoes enhance jungle walks. Colón’s cultural charm offers a vibrant Panamanian stop. Cruise travelers enjoy a mix of canal engineering and indigenous heritage, making Colón an engaging destination for exploration. (126 words)
Cartagena, Colombia, offers docking at Cartagena Port. Travelers explore San Felipe Castle and Old Town’s colorful streets. Excursions include Rosario Islands snorkeling. Local markets sell arepas. The peak season, December to April, brings warm weather for coastal tours. Photography captures colonial walls and Caribbean vistas. Dining onboard includes sancocho, a Colombian favorite. Souvenirs, like emerald crafts, are sold in ship shops. Briefings cover Spanish colonial history. Light clothing and sun protection suit the tropical climate, while comfortable shoes enhance historic walks. Cartagena’s cultural charm offers a vibrant Colombian stop. Cruise travelers enjoy a mix of historic fortresses and scenic islands, making Cartagena an engaging destination for exploration. (126 words)