The September 21, 2025 cruise on the Odyssey of the Seas departs from Civitavecchia (Rome), Italy. On this 7 Night Greek Isles (Rome Roundtrip) sailing, the ship will visit a total of 5 different cruise port destinations, including its departure port. The Odyssey of the Seas sets sail on Sunday, Sep 21st and returns on Sunday, Sep 28th.
Sep 21st - Sep 28th
Royal Caribbean Cruise Line
from Civitavecchia (Rome), Italy
Cruise Price - Historic & Current
The graph below tracks historic price of the Odyssey of the Seas cruise ship departing September 21, 2025. The most recent price for this sailing starts at $1,361 ($195 per night) for an Inside Cabin. Compared to the average price of $1,129 ($162 per night), this represents a recent increase of 20%.
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The Odyssey of the Seas has a construction date of 2021 and a total size of 169,379 gross tons. The ship measures 1,139 feet (347 meters) in length. Odyssey of the Seas is included in Royal Caribbean’s Quantum-Ultra Class. At full capacity, the Odyssey of the Seas holds 5,835 passengers. That includes 4,284 cruise vacationers and 1,551 staff members. The Odyssey of the Seas total number of staterooms is 2,110.
To see how this compares, click through to see Odyssey of the Seas age and stats vs all Royal Caribbean ships. There you’ll find graphs showing length, capacity, tonnage and more for this ship vs all in the fleet.
To check out the ship from top to bottom, click here for Odyssey of the Seas Deck Plans.
Odyssey of the Seas - September 21, 2025 - 7 Nights
Day | Date | Port |
---|---|---|
1 | Sep 21st | Civitavecchia (Rome), Italy |
2 | Sep 22nd | At Sea |
3 | Sep 23rd | Santorini, Greece |
4 | Sep 24th | Kusadasi (Ephesus), Turkey |
5 | Sep 25th | Mykonos, Greece |
6 | Sep 26th | At Sea |
7 | Sep 27th | Naples, Italy |
8 | Sep 28th | Civitavecchia (Rome), Italy |
Cruise Itinerary
The Odyssey of the Seas sails on September 21, 2025 for a 7 Night Greek Isles (Rome Roundtrip). The ship will depart the port of Civitavecchia (Rome), Italy at 5:00 PM and will return to the port of Civitavecchia (Rome), Italy on Sep 28th at 5:00 AM. During the 8-day journey, the Odyssey of the Seas will visit 4 additional ports and will spend 2 days at sea.
Civitavecchia is just moments from Rome, Italy's Eternal City. One of the most geographically perfect ports in the world, Civitavecchia boasts a number of compelling area attractions. Stroll through the streets of the medieval town of Tarquinia. View the resplendent Madonnina at the Resort of Pantano.
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
With its steep volcanic flanks looming straight up from the sea, and the tiny white village of Thira clinging high atop the cliffs, Santorini is perhaps the most breathtaking and legendary of all the Greek Isles. To the south is Akrotiri, where recent Minoan excavations support the theories that Santorini might be the fabled lost continent of Atlantis.
This charming, picturesque resort where Antony and Cleopatra used to vacation is best known as the port for the ancients ruins of Ephesus - one of the world's most wondrous archaeological sites. Explorations should include such masterpieces as the Great Amphitheatre, where St. Paul addressed the Ephesians, the Library of Celsus, and the temples of Athena and Apollo - all connected by marble streets rutted by the wheels of countless chariots.
The narrow passageways of Mykonos are a twisted maze of whitewashed houses, miniature churches, lazy windmills, and tiny cafes serving up Greek specialties. Sample the freshest squid or lobster just snatched from the blue Aegean Sea, or shop for typical flokati rugs.
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
One of the most spectacular bays in the world lies in the shadow of Mt. Vesuvius. Visit the San Carlo Opera House and the cathedral of San Janarious, or tour the ancient ruins in the Roman cities of Pompeii and Herculaneum.
Civitavecchia is just moments from Rome, Italy's Eternal City. One of the most geographically perfect ports in the world, Civitavecchia boasts a number of compelling area attractions. Stroll through the streets of the medieval town of Tarquinia. View the resplendent Madonnina at the Resort of Pantano.