Embarkation day. MSC Opera sails at 7:00 PM.

MSC Opera
October 29, 2026
25-Night Msc Grand Voyages aboard MSC Opera · Departing October 29, 2026 from the Port of Civitavecchia, Italy.
MSC Opera October 29, 2026 Cruise Overview
MSC Opera leaves Civitavecchia (Rome), Italy on Thursday, October 29, 2026 at 7:00 PM and ends in La Romana, Dominican Republic on Monday, November 23 at 9:00 AM: 25 nights with 14 ports of call (Genoa Portofino Italy, Livorno, Marseille, Barcelona, Tangier, St. John's, Philipsburg, Basseterre, La Romana, Catalina Island, Bridgetown, Fort-De-France, Pointe-A-Pitre and Tortola) and 10 days at sea. It is the only upcoming departure of this itinerary on MSC Opera. The lowest fare today is $4,759 per person for a balcony cabin (about $190 a night). Since we started tracking it in August 2025, the balcony fare has ranged from $3,078 to $5,232; today’s is $1,681 above the lowest. October averages 84°F highs and 69°F lows across the ports on this route.
The itinerary safety score for this sailing is 6.8 out of 10, averaged across 15 ports.
MSC Opera October 29, 2026 Roll Call
MSC Opera October 29, 2026 Price & Tracking
The graph below tracks historic price of the MSC Opera cruise ship departing October 29, 2026. The most recent price for this sailing starts at $4,759 ($191 per night) for a Balcony Cabin. Compared to the average price of $4,003 ($161 per night), this represents a recent increase of 19%.
MSC Opera cruise departing October 29, 2026 — 25-night itinerary. Current Balcony Cabin price: $4,759 ($191 per night). Average price: $4,003.
Prices change often and may differ at checkout. Click to see the latest available price.
Get an email notification when the price of the MSC Opera – October 29, 2026 drops below $4,759 for a balcony cabin.
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25 Night Msc Grand Voyages (Rome To La Romana) Cruise Map
25 Night Msc Grand Voyages (Rome To La Romana) Port List
At sea
Day at sea aboard the Opera — explore the ship's signature dining, entertainment, and onboard activities.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
At sea
Day at sea aboard the Opera.
25 Night Msc Grand Voyages (Rome To La Romana) Weather Forecast
Most Popular Civitavecchia Shore Excursions
Independent shore excursions in every port on this MSC Opera itinerary, booked directly with the operator who runs them. We flag the ones that guarantee you're back on board before the gangway lifts.
Private Transfer from the Port of Civitaveccha to Hotel in Rome (Post Cruise)
Small Group Highlights of Rome
Exclusive Best of Rome
Catacombs of San Sebastiano and Callisto Guided Tour
Classical Rome
Rome's Colosseum and Imperial Forum
The Dying City and the Sacred Wood
Private Transfer from Fiumicino Airport to Port of Civitavecchia (Pre-Cruise)
These are the eight most reviewed. Civitavecchia has plenty more — browse the full catalogue and book direct with the operator.
SEE ALL CIVITAVECCHIA EXCURSIONSPricing and availability are provided by the operator. Booking happens on their own site — MSC Opera sails October 29, 2026, and Gangwaze earns a commission at no extra cost to you.
Itinerary Safety Score
Based on comprehensive research of cruise port safety information, including recent crime reports, travel advisories, Global Peace Index rankings, and specific port security concerns, we've created a "safety score" for each cruise port stop. The overall rating below represents a combined score for your specific cruise itinerary.
Scores combine recent crime reports, government travel advisories, Global Peace Index rankings, and port-specific security incidents. Refreshed monthly.
Civitavecchia is generally safe, but travelers should remain vigilant against petty theft and scams in crowded areas and near attractions.
Genoa and Portofino are generally safe for cruise travelers, but vigilance against petty crime like pickpocketing is advised.
Travelers should remain vigilant against pickpocketing and bag snatching in crowded areas while enjoying the attractions in Livorno and Florence.
Travelers in Marseille should stay vigilant in certain neighborhoods due to higher crime rates and secure their belongings in crowded areas.
Travelers should stay vigilant against pickpocketing in crowded areas and secure their belongings to ensure safety while enjoying the city.
Travelers should remain vigilant in Tangier, especially in the medina, to avoid petty crime and harassment while exploring the city.
St. John's is generally safe for travelers, but vigilance is advised due to potential petty theft and risks in certain neighborhoods after dark.
Philipsburg is generally safe for cruise travelers, but remain vigilant against petty theft in crowded areas and secure personal belongings.
Basseterre is generally safe for cruise travelers, but it's wise to stay vigilant against petty theft and avoid poorly lit areas at night.
In La Romana, stay vigilant and take precautions in less populated areas to minimize crime risks while enjoying the attractions.
Catalina Island is a low-crime, secure destination with organized tours and good security measures, ensuring a safe experience for travelers.
Travelers should stay vigilant in busy areas of Bridgetown, as petty crime and scams can occur, and secure personal belongings.
Fort-De-France is generally safe for tourists, but staying vigilant, especially in crowded areas, is essential to avoid petty theft.
Pointe-à-Pitre is generally safe for cruise travelers, but remain vigilant against petty crime, especially in less populated areas at night.
Tortola is generally safe for tourists, but visitors should stay vigilant and exercise caution, especially after dark.
MSC Opera Ship Overview
The MSC Opera has a construction date of 2004 and a total size of 65,591 gross tons. The ship measures 902 feet in length. MSC Opera is included in MSC's Lirica class. At full capacity, the Opera holds 2,679 passengers. That includes 1,951 cruise vacationers and 728 staff members. The Opera total number of staterooms is 1,068.
More MSC Opera cruises
Hop to the previous or next sailing on this ship, or browse the full schedule.























