

The November 23, 2026 cruise on the MSC Musica departs from Santo Tomas De Castilla, Guatemala. On this South America from Santos sailing, the ship will visit a total of 2 cruise port destinations, including its departure port. The MSC Musica sets sail on Monday, Nov 23rd and returns on Thursday, Nov 26th.
The graph below tracks historic price of the MSC Musica cruise ship departing November 23, 2026. The most recent price for this sailing starts at $345 ($115 per night) for an Inside Cabin. Compared to the average price of $371 ($124 per night), this represents a recent decrease of 7%.
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MSC Musica - November 23, 2026 - 3 Nights
| Day | Date | Port |
|---|---|---|
| 1 | Nov 22nd | Santo Tomas De Castilla, Guatemala |
| 2 | Nov 23rd | At Sea |
| 3 | Nov 25th | Buzios, Brazil |
| 5 | Nov 27th | Santo Tomas De Castilla, Guatemala |
The MSC Musica sails on November 23, 2026 for a South America from Santos. The ship will depart the port of Santo Tomas De Castilla, Guatemala at 5:00 PM and will return to the port of Santo Tomas De Castilla, Guatemala on Nov 26th at 8:00 AM. During the 4-day journey, the MSC Musica will visit 1 additional port and will spend 1 days at sea.
Based on my comprehensive research of cruise port safety information, including recent crime reports, travel advisories, Global Peace Index rankings, and specific port security concerns, we've created a "safety score" for each cruise port stop. The overall rating below represents a combined score for your specific cruise itinerary.

The Musica has a construction date of 2006 and a total size of 92,409 gross tons. The ship measures 964 feet (294 meters) in length. MSC Musica is included in MSC’s Musica Class. At full capacity, the MSC Musica holds 3,537 passengers. That includes 2,550 cruise vacationers and 987 staff members. The Musica total number of staterooms is 1,335.
To see how this compares, click through to see MSC Musica age and stats vs all MSC ships. There you’ll find graphs showing length, capacity, tonnage and more for this ship vs all in the fleet.
To check out the ship from top to bottom, click here for MSC Musica Deck Plans.
Santo Tomas de Castilla, Guatemala, offers docking at Santo Tomas Port. Travelers explore Quiriguá ruins and Rio Dulce. Excursions include Livingston’s Garifuna culture. Local markets sell tamales. The peak season, December to April, brings dry weather for coastal tours. Photography captures Mayan stelae and Caribbean vistas. Dining onboard includes pepián, a Guatemalan favorite. Souvenirs, like textile crafts, are sold in ship shops. Briefings cover Mayan history. Light clothing and sun protection suit the tropical climate, while sturdy shoes enhance jungle walks. Santo Tomas’ cultural charm offers a vibrant Guatemalan stop. Cruise travelers enjoy a mix of ancient ruins and scenic rivers, making Santo Tomas an engaging destination. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Buzios, Brazil, anchors offshore with tenders to Canto Beach, a 5-minute ride to downtown, population 30,000. Travelers stroll Rua das Pedras for boutiques. Praia da Ferradura offers snorkeling. Local markets sell cachaça. Excursions to Arraial do Cabo, 1 hour east, explore beaches. Peak season December to March; taxis 10-20 BRL. Dining includes moqueca at seaside restaurants. Souvenirs feature Havaianas flip-flops.
Santo Tomas de Castilla, Guatemala, offers docking at Santo Tomas Port. Travelers explore Quiriguá ruins and Rio Dulce. Excursions include Livingston’s Garifuna culture. Local markets sell tamales. The peak season, December to April, brings dry weather for coastal tours. Photography captures Mayan stelae and Caribbean vistas. Dining onboard includes pepián, a Guatemalan favorite. Souvenirs, like textile crafts, are sold in ship shops. Briefings cover Mayan history. Light clothing and sun protection suit the tropical climate, while sturdy shoes enhance jungle walks. Santo Tomas’ cultural charm offers a vibrant Guatemalan stop. Cruise travelers enjoy a mix of ancient ruins and scenic rivers, making Santo Tomas an engaging destination. (126 words)