

The October 4, 2025 cruise on the Radiance of the Seas departs from San Diego, California. On this 16 Night Panama Canal (San Diego To Ft. Lauderdale) sailing, the ship will visit a total of 10 cruise port destinations, including its departure port. The Radiance of the Seas sets sail on Saturday, Oct 4th and returns on Monday, Oct 20th.
The graph below tracks historic price of the Radiance of the Seas cruise ship departing October 4, 2025. The most recent price for this sailing starts at $2,249 ($141 per night) for an Inside Cabin. Compared to the average price of $2,739 ($172 per night), this represents a recent decrease of 18%.
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Radiance of the Seas - October 4, 2025 - 16 Nights
| Day | Date | Port |
|---|---|---|
| 1 | Oct 4th | San Diego, California |
| 2 | Oct 5th | At Sea |
| 3 | Oct 6th | Cabo San Lucas, Mexico |
| 4 | Oct 7th | Mazatlan, Mexico |
| 5 | Oct 8th | At Sea |
| 6 | Oct 9th | At Sea |
| 7 | Oct 10th | Puerto Quetzal, Guatemala |
| 8 | Oct 11th | At Sea |
| 9 | Oct 12th | Puntarenas, Costa Rica |
| 10 | Oct 13th | At Sea |
| 11 | Oct 14th | Panama Canal Transit |
| 12 | Oct 15th | Colon, Panama |
| 13 | Oct 16th | Cartagena, Colombia |
| 14 | Oct 17th | At Sea |
| 15 | Oct 18th | George Town, Grand Cayman |
| 16 | Oct 19th | At Sea |
| 17 | Oct 20th | Fort Lauderdale (Port Everglades), Florida |
The Radiance of the Seas sails on October 4, 2025 for a 16 Night Panama Canal (San Diego To Ft. Lauderdale). The ship will depart the port of San Diego, California at 4:00 PM and will return to the port of Fort Lauderdale (Port Everglades), Florida on Oct 20th at 6:00 AM. During the 17-day journey, the Radiance of the Seas will visit 9 additional ports and will spend 7 days at sea.
Based on my comprehensive research of cruise port safety information, including recent crime reports, travel advisories, Global Peace Index rankings, and specific port security concerns, we've created a "safety score" for each cruise port stop. The overall rating below represents a combined score for your specific cruise itinerary.

The Radiance of the Seas has a construction date of 2001 and a total size of 90,900 gross tons. The ship measures 962 feet (293 meters) in length. Radiance of the Seas is included in Royal Caribbean’s Radiance Class. At full capacity, the Radiance of the Seas holds 3,033 passengers. That includes 2,139 cruise vacationers and 894 staff members. The Radiance of the Seas total number of staterooms is 1,071.
To see how this compares, click through to see Radiance of the Seas age and stats vs all Royal Caribbean ships. There you’ll find graphs showing length, capacity, tonnage and more for this ship vs all in the fleet.
To check out the ship from top to bottom, click here for Radiance of the Seas Deck Plans.
San Diego, California, offers docking at San Diego Port. Travelers explore Balboa Park and Gaslamp Quarter. Excursions visit La Jolla’s sea lions. Local markets sell fish tacos. The peak season, May to September, brings mild weather for coastal tours. Photography captures Spanish architecture and Pacific vistas. Dining onboard includes carne asada, a Californian favorite. Souvenirs, like surf-themed crafts, are sold in ship shops. Briefings cover Kumeyaay history. Light clothing and sun protection suit the temperate climate, while comfortable shoes enhance park walks. San Diego’s urban charm offers a vibrant American stop. Cruise travelers enjoy a mix of cultural parks and scenic coasts, making San Diego an engaging destination. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Cabo San Lucas, Mexico, offers docking at Cabo San Lucas Port. Travelers explore El Arco and Lover’s Beach. Excursions include snorkeling at Santa Maria Cove. Local markets sell fish tacos. The peak season, November to April, brings warm weather for coastal tours. Photography captures rock formations and Pacific vistas. Dining onboard includes ceviche, a Mexican favorite. Souvenirs, like silver crafts, are sold in ship shops. Briefings cover Baja history. Light clothing and sun protection suit the arid climate, while water shoes enhance reef exploration. Cabo San Lucas’ coastal allure offers a vibrant Mexican stop. Cruise travelers enjoy a mix of iconic landmarks and marine adventures, making Cabo an engaging destination. (126 words)
Mazatlan, Mexico, offers docking at Mazatlan Port. Travelers explore Old Town and El Faro Lighthouse. Excursions include snorkeling at Deer Island. Local markets sell shrimp tacos. The peak season, November to April, brings warm weather for coastal tours. Photography captures colonial plazas and Pacific vistas. Dining onboard includes aguachile, a Mexican favorite. Souvenirs, like pottery crafts, are sold in ship shops. Briefings cover Sinaloa history. Light clothing and sun protection suit the tropical climate, while water shoes enhance beach exploration. Mazatlan’s coastal charm offers a vibrant Mexican stop. Cruise travelers enjoy a mix of historic districts and scenic beaches, making Mazatlan an engaging destination for exploration. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Puerto Quetzal, Guatemala, offers docking at Puerto Quetzal Port. Travelers explore Antigua’s colonial streets and Pacaya Volcano. Excursions include coffee plantation tours. Local markets sell tamales. The peak season, December to April, brings dry weather for coastal tours. Photography captures cobblestone plazas and Pacific vistas. Dining onboard includes pepián, a Guatemalan favorite. Souvenirs, like textile crafts, are sold in ship shops. Briefings cover Mayan history. Light clothing and sun protection suit the tropical climate, while sturdy shoes enhance volcano hikes. Puerto Quetzal’s cultural charm offers a vibrant Guatemalan stop. Cruise travelers enjoy a mix of colonial heritage and scenic volcanoes, making Puerto Quetzal an engaging destination. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Puntarenas, Costa Rica, offers docking at Puntarenas Port. Travelers explore Paseo de los Turistas and Carara National Park. Excursions include zip-lining in Monteverde. Local markets sell gallo pinto. The peak season, December to April, brings dry weather for coastal tours. Photography captures mangroves and Pacific vistas. Dining onboard includes casado, a Costa Rican favorite. Souvenirs, like coffee crafts, are sold in ship shops. Briefings cover Tico history. Light clothing and sun protection suit the tropical climate, while sturdy shoes enhance rainforest hikes. Puntarenas’ natural charm offers a vibrant Costa Rican stop. Cruise travelers enjoy a mix of wildlife and scenic coasts, making Puntarenas an engaging destination. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Panama Canal Transit, Panama, offers scenic cruising without docking. Travelers view Gatun Locks and Centennial Bridge from the ship. Excursions include canal history tours. No facilities exist; provisions are ship-based. The peak season, December to April, brings dry weather for canal cruising. Photography captures engineering marvels and Pacific vistas. Dining onboard includes arroz con pollo, a Panamanian favorite. Souvenirs, like molas, are sold in ship shops. Briefings cover canal history. Light clothing and sun protection suit the tropical climate, while binoculars enhance lock viewing. Panama Canal’s industrial allure offers a vibrant stop. Cruise travelers enjoy a mix of engineering feats and scenic waterways, making the Panama Canal an engaging destination. (126 words)
Colón, Panama, offers docking at Colón Port. Travelers explore Gatun Locks and Fort San Lorenzo. Excursions include Emberá village tours. Local markets sell sancocho. The peak season, December to April, brings dry weather for coastal tours. Photography captures canal locks and Caribbean vistas. Dining onboard includes arroz con pollo, a Panamanian favorite. Souvenirs, like molas, are sold in ship shops. Briefings cover Kuna history. Light clothing and sun protection suit the tropical climate, while sturdy shoes enhance jungle walks. Colón’s cultural charm offers a vibrant Panamanian stop. Cruise travelers enjoy a mix of canal engineering and indigenous heritage, making Colón an engaging destination for exploration. (126 words)
Cartagena, Colombia, offers docking at Cartagena Port. Travelers explore San Felipe Castle and Old Town’s colorful streets. Excursions include Rosario Islands snorkeling. Local markets sell arepas. The peak season, December to April, brings warm weather for coastal tours. Photography captures colonial walls and Caribbean vistas. Dining onboard includes sancocho, a Colombian favorite. Souvenirs, like emerald crafts, are sold in ship shops. Briefings cover Spanish colonial history. Light clothing and sun protection suit the tropical climate, while comfortable shoes enhance historic walks. Cartagena’s cultural charm offers a vibrant Colombian stop. Cruise travelers enjoy a mix of historic fortresses and scenic islands, making Cartagena an engaging destination for exploration. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
George Town, Grand Cayman, offers docking at George Town Port. Travelers explore Seven Mile Beach and Stingray City. Excursions include snorkeling at Coral Gardens. Local markets sell jerk chicken. The peak season, December to April, brings warm weather for coastal tours. Photography captures turquoise waters and Caribbean vistas. Dining onboard includes conch chowder, a Caymanian favorite. Souvenirs, like turtle crafts, are sold in ship shops. Briefings cover Taino history. Light clothing and sun protection suit the tropical climate, while water shoes enhance reef exploration. George Town’s coastal allure offers a vibrant Cayman stop. Cruise travelers enjoy a mix of pristine beaches and marine adventures, making George Town an engaging destination. (126 words)
Take advantage of the many on board activites during your day at sea. You'll have more than enough to fill your day!
Fort Lauderdale (Port Everglades), Florida, offers docking at Port Everglades. Travelers explore Las Olas Boulevard and Everglades tours. Excursions include airboat rides. Local markets sell conch fritters. The peak season, December to April, brings warm weather for coastal tours. Photography captures canals and Atlantic vistas. Dining onboard includes stone crab, a Floridian favorite. Souvenirs, like seashell crafts, are sold in ship shops. Briefings cover Seminole history. Light clothing and sun protection suit the subtropical climate, while comfortable shoes enhance city walks. Fort Lauderdale’s urban charm offers a vibrant American stop. Cruise travelers enjoy a mix of scenic waterways and natural adventures, making Fort Lauderdale an engaging destination for exploration. (126 words)