Odyssey of the Seas itinerary map for September 21, 2025
Odyssey of the Seas

7 Night Greek Isles on Royal Caribbean Odyssey of the Seas

September 21, 2025

Odyssey of the Seas September 21, 2025

The Odyssey of the Seas September 21, 2025 cruise departs from Civitavecchia (Rome), Italy. On this 7 Night Greek Isles (Rome Roundtrip) sailing, the Odyssey of the Seas will visit a total of 5 cruise port destinations, including its departure port. The ship sets sail on Sunday, Sep 21st and returns on Sunday, Sep 28th, 2025.

Cruise Length
7
Night Cruise
Departure Port
Civitavecchia
Italy
Port Stops
5
Sea Days
2
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Cruise Price - Odyssey of the Seas September 21, 2025

Odyssey of the Seas · September 21, 2025

The graph below tracks historic price of the Odyssey of the Seas cruise ship departing September 21, 2025. The most recent price for this sailing starts at $2,468 ($353 per night) for an Inside Cabin. Compared to the average price of $2,103 ($301 per night), this represents a recent increase of 17%.

🛏️
Inside
$2,468
🌊
Oceanview
$2,433
🌅
Balcony
$2,873
👑
Suite
$2,993

Price History – Odyssey of the Seas September 21, 2025

inside cabin
Odyssey of the Seas
September 21, 2025
$2,468
17% vs avg: $2,103

Prices change often and may differ at checkout. Click to see the latest available price.

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Cruise Itinerary Map - 7 Night Greek Isles (Rome Roundtrip)

Odyssey of the Seas · September 21, 2025

The Odyssey of the Seas sails on September 21, 2025 for a 7 Night Greek Isles (Rome Roundtrip). The ship will depart the port of Civitavecchia (Rome), Italy at 5:00 PM and will return to the port of Civitavecchia (Rome), Italy on Sep 28th at 5:00 AM. During the 8-day journey, the Odyssey of the Seas will visit 4 additional ports and will spend 2 days at sea.

Cruise itinerary route

7 Night Greek Isles (Rome Roundtrip)

  • SEP21
    Civitavecchia (Rome), Italy
    Civitavecchia (Rome), Italy
    A: — - D: 5:00 PM
  • SEP22
    At Sea
    At Sea
    A: — - D: —
  • SEP23
    Santorini, Greece
    Santorini, Greece
    A: 11:00 AM - D: 10:00 PM
  • SEP24
    Kusadasi (Ephesus), Turkey
    Kusadasi (Ephesus), Turkey
    A: 9:00 AM - D: 6:00 PM
  • SEP25
    Mykonos, Greece
    Mykonos, Greece
    A: 7:00 AM - D: 6:00 PM
  • SEP26
    At Sea
    At Sea
    A: — - D: —
  • SEP27
    Naples, Italy
    Naples, Italy
    A: 7:00 AM - D: 6:00 PM
  • SEP28
    Civitavecchia (Rome), Italy
    Civitavecchia (Rome), Italy
    A: 5:00 AM - D: —
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Cruise Ports

September 21, 2025 · 7 Night Greek Isles (Rome Roundtrip)

Civitavecchia (Rome), Italy
Day 1•Sunday, Sep 21

Civitavecchia (Rome), Italy

Arrival: —•Departure: 5:00 PM

Civitavecchia (Rome), Italy, offers docking at Civitavecchia Port with excursions to Rome. Travelers explore Colosseum and Pantheon. Excursions visit Vatican City’s Sistine Chapel. Local markets sell gelato. The peak season, April to October, brings warm weather for city tours. Photography captures ancient ruins and Tyrrhenian vistas. Dining onboard includes carbonara, an Italian favorite. Souvenirs, like Murano glass, are sold in ship shops. Briefings cover Roman history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance historic walks. Civitavecchia’s cultural gateway offers a vibrant Italian stop. Cruise travelers enjoy a mix of ancient landmarks and scenic coasts, making Civitavecchia an engaging destination.

Port Info LinkPort Excursions Link
At Sea
Day 2•Monday, Sep 22

At Sea

Arrival: 12:00 AM•Departure: 11:59 PM

Enjoy onboard activities and ocean views during this sea day.

Santorini, Greece
Day 3•Tuesday, Sep 23

Santorini, Greece

Arrival: 11:00 AM•Departure: 10:00 PM

Santorini, Greece, offers docking at Fira Port with tenders to shore. Travelers explore Oia’s blue-domed churches and Thera ruins. Excursions include sailing to Nea Kameni. Local markets sell fava beans. The peak season, May to September, brings warm weather for island tours. Photography captures caldera views and Aegean vistas. Dining onboard includes moussaka, a Greek favorite. Souvenirs, like volcanic crafts, are sold in ship shops. Briefings cover Minoan history. Light clothing and sun protection suit the Mediterranean climate, while sturdy shoes enhance cliff walks. Santorini’s iconic charm offers a vibrant Greek stop. Cruise travelers enjoy a mix of stunning views and ancient ruins, making Santorini an engaging destination.

Port Info LinkPort Excursions Link
Kusadasi (Ephesus), Turkey
Day 4•Wednesday, Sep 24

Kusadasi (Ephesus), Turkey

Arrival: 9:00 AM•Departure: 6:00 PM

Kusadasi (Ephesus), Turkey, offers docking at Kusadasi Port with excursions to Ephesus. Travelers explore Ephesus ruins and Artemis Temple. Excursions visit Virgin Mary’s House. Local markets sell baklava. The peak season, April to October, brings warm weather for coastal tours. Photography captures ancient ruins and Aegean vistas. Dining onboard includes kebabs, a Turkish favorite. Souvenirs, like carpet crafts, are sold in ship shops. Briefings cover Hellenistic history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance ruin walks. Kusadasi’s historic charm offers a vibrant Turkish stop. Cruise travelers enjoy a mix of archaeological sites and scenic coasts, making Kusadasi an engaging destination.

Port Info LinkPort Excursions Link
Mykonos, Greece
Day 5•Thursday, Sep 25

Mykonos, Greece

Arrival: 7:00 AM•Departure: 6:00 PM

Mykonos, Greece, offers docking at Mykonos Port. Travelers explore Little Venice and Mykonos Windmills. Excursions include Delos Island ruins. Local markets sell loukoumades. The peak season, May to September, brings warm weather for coastal tours. Photography captures whitewashed streets and Aegean vistas. Dining onboard includes souvlaki, a Greek favorite. Souvenirs, like ceramic crafts, are sold in ship shops. Briefings cover Cycladic history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance island walks. Mykonos’ picturesque charm offers a vibrant Greek stop. Cruise travelers enjoy a mix of historic ruins and scenic beaches, making Mykonos an engaging destination for exploring Greece’s Cyclades.

Port Info LinkPort Excursions Link
At Sea
Day 6•Friday, Sep 26

At Sea

Arrival: 12:00 AM•Departure: 11:59 PM

Enjoy onboard activities and ocean views during this sea day.

Naples, Italy
Day 7•Saturday, Sep 27

Naples, Italy

Arrival: 7:00 AM•Departure: 6:00 PM

Naples, Italy, offers docking at Naples Port. Travelers explore Pompeii ruins and Royal Palace. Excursions visit Capri’s Blue Grotto. Local markets sell margherita pizza. The peak season, April to October, brings warm weather for coastal tours. Photography captures ancient ruins and Tyrrhenian vistas. Dining onboard includes spaghetti alle vongole, an Italian favorite. Souvenirs, like cameo crafts, are sold in ship shops. Briefings cover Roman history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance historic walks. Naples’ cultural charm offers a vibrant Italian stop. Cruise travelers enjoy a mix of archaeological sites and scenic islands, making Naples an engaging destination for exploration.

Port Info LinkPort Excursions Link
Civitavecchia (Rome), Italy
Day 8•Sunday, Sep 28

Civitavecchia (Rome), Italy

Arrival: 5:00 AM•Departure: —

Civitavecchia (Rome), Italy, offers docking at Civitavecchia Port with excursions to Rome. Travelers explore Colosseum and Pantheon. Excursions visit Vatican City’s Sistine Chapel. Local markets sell gelato. The peak season, April to October, brings warm weather for city tours. Photography captures ancient ruins and Tyrrhenian vistas. Dining onboard includes carbonara, an Italian favorite. Souvenirs, like Murano glass, are sold in ship shops. Briefings cover Roman history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance historic walks. Civitavecchia’s cultural gateway offers a vibrant Italian stop. Cruise travelers enjoy a mix of ancient landmarks and scenic coasts, making Civitavecchia an engaging destination.

Port Info LinkPort Excursions Link

Weather Forecast

Odyssey of the Seas - September 21, 2025 Weather Forecast

Average monthly weather for your cruise ports

Civitavecchia (Rome), Italy

⛅

September

Typical Weather

86°F

Average High

56°F

Average Low

Rainfall

0.10in

Daily average

3.0 in monthly total

Shore Excursions

Explore the most popular excursion options at each port.

From beach breaks and snorkeling to local food tours and cultural landmarks, these shore excursions help you make the most of every stop. Browse by port below to compare top-rated options and plan your day before you board.

See all Civitavecchia Shore Tours

Itinerary Safety Score

Based on comprehensive research of cruise port safety information, including recent crime reports, travel advisories, Global Peace Index rankings, and specific port security concerns, we've created a "safety score" for each cruise port stop. The overall rating below represents a combined score for your specific cruise itinerary.

Itinerary Safety Rank
72 / 100
safer than 72% of all cruises
72
7
/ 10
Civitavecchia (Rome), Italy
Civitavecchia
Civitavecchia is generally safe, but travelers should remain vigilant against petty theft and scams in crowded areas and near attractions.
9
/ 10
Santorini, Greece
Santorini
Santorini is safe for travelers, but they should stay vigilant in crowded areas for pickpocketing and be cautious of traffic hazards.
7
/ 10
Kusadasi (Ephesus), Turkey
Kusadasi
Kusadasi is generally safe for travelers, but they should remain vigilant against petty crime and safeguard personal belongings.
8
/ 10
Mykonos, Greece
Mykonos
Travelers in Mykonos should remain vigilant against petty theft and scams, especially in crowded areas during peak season.
6
/ 10
Naples, Italy
Naples
Travelers in Naples should stay vigilant against petty crime and be cautious of traffic while exploring the city.

Cruise Ship

Odyssey of the Seas

⚓ Tonnage

167,704

vs avg 162,993

🛠️ Year Built

2,021

vs avg 2,010

📏 Length (ft)

1,138

vs avg 1,085

👥 Passenger Count

4,284

vs avg 4,184

The Odyssey of the Seas has a construction date of 2021 and a total size of 167,704 gross tons. The ship measures 1,138 feet in length. Odyssey of the Seas is included in Royal Caribbean’s Quantum-Ultra class. At full capacity, the Odyssey of the Seas holds 4,284 passengers. That includes 2,672 cruise vacationers and 1,612 staff members. The Odyssey of the Seas total number of staterooms is 2,110.

Click above for more Odyssey of the Seas stats, tips, imagery, and more.

  • 📊Size comparison chart against other ships
  • 🍸Bars, restaurants, and venue highlights
  • 🛠️Renovation and dry-dock schedule
  • ❓FAQ's about Odyssey of the Seas

Also of interest:

Odyssey of the Seas Deck PlansOdyssey of the Seas Cabin SearchOdyssey of the Seas Health Score

Odyssey of the Seas September 21, 2025 FAQ

How many nights is the Odyssey of the Seas sailing on September 21, 2025?▾

This is a 7-night cruise itinerary departing from Civitavecchia (Rome), Italy.

What ports does the Odyssey of the Seas visit on the September 21, 2025 cruise?▾

This route includes rome-italy, santorini-greece, kusadasi-turkey, mykonos-greece, naples-italy.

How many sea days are included on this Odyssey of the Seas September 21, 2025 itinerary?▾

This itinerary includes 2 sea days.

Who is the cruise director for the Odyssey of the Seas sailing on September 21, 2025?▾

Cruise director assignment data is not currently available for this sail date.

How is the itinerary safety score calculated for this cruise?▾

The itinerary safety score combines port-level safety indicators such as travel advisories, local risk signals, and historical context into a single overall score for this specific route.

Can I track price drops for this Odyssey of the Seas itinerary?▾

Yes — use the price tracking opt-in on this page to get updates when cabin prices change for this sailing.

Last Updated: Apr 22, 2026