MSC Opera itinerary map for September 22, 2025 (7 nights)

MSC Opera — September 22, 20257-Night Eastern Mediterranean on MSC

This 7-night cruise aboard the Opera departs from Piraeus (Athens), Greece on Monday, September 22, 2025 and returns on Monday, Sep 29th. September weather across this route averages 99°/60°F.

The itinerary safety score for this sailing is 7.0 out of 10, averaged across 5 ports.

Cruise Length

Night Cruise

Departure Port

Piraeus

Greece

Port Stops

Sea Days

Cruise Itinerary Map - 7 Night Eastern Mediterranean (Athens Roundtrip)

MSC Opera · September 22, 2025

The MSC Opera sails on September 22, 2025 for a 7 Night Eastern Mediterranean (Athens Roundtrip). The ship will depart the port of Piraeus (Athens), Greece at 8:00 PM and will return to the port of Piraeus (Athens), Greece on Sep 29th at 7:00 AM. During the 8-day journey, the MSC Opera will visit 4 additional ports and will spend 2 days at sea.

Cruise itinerary route

7 Night Eastern Mediterranean (Athens Roundtrip)

SEP22
Piraeus (Athens), Greece
A: — - D: 8:00 PM
SEP23
Kos, Greece
A: 9:00 AM - D: 7:00 PM
SEP24
Rhodes, Greece
A: 8:00 AM - D: 10:00 PM
SEP25
Bodrum, Turkey
A: 7:00 AM - D: 5:00 PM
SEP26
At Sea
A: — - D: —
SEP27
Bari, Italy
A: 7:00 AM - D: 7:00 PM
SEP28
At Sea
A: — - D: —
SEP29
Piraeus (Athens), Greece
A: 7:00 AM - D: —

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Cruise Ports

September 22, 2025 · 7 Night Eastern Mediterranean (Athens Roundtrip)

Day 1•Monday, Sep 22

Piraeus (Athens), Greece

Arrival: —•Departure: 8:00 PM

Piraeus (Athens), Greece, offers docking at Piraeus Port with excursions to Athens. Travelers explore Acropolis and Parthenon. Excursions visit Cape Sounion. Local markets sell souvlaki. The peak season, April to October, brings warm weather for city tours. Photography captures ancient ruins and Aegean vistas. Dining onboard includes moussaka, a Greek favorite. Souvenirs, like olive oil, are sold in ship shops. Briefings cover Hellenic history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance historic walks. Piraeus’ cultural gateway offers a vibrant Greek stop. Cruise travelers enjoy a mix of iconic landmarks and scenic coasts, making Piraeus an engaging destination for exploration.

Port Info Link Port Excursions Link

Day 2•Tuesday, Sep 23

Kos, Greece

Arrival: 9:00 AM•Departure: 7:00 PM

Kos, Greece, has docking at Kos Port. Travelers explore Asklepion’s ancient healing site and Hippocrates’ plane tree. Excursions visit Zia’s mountain village. Local markets sell thyme honey. The peak season, May to September, brings warm weather. Photography captures ancient ruins and Aegean vistas. Dining onboard includes souvlaki, a Greek favorite. Souvenirs, like ceramic tiles, are sold in ship shops. Briefings cover ancient Greek history. Light clothing and sun protection suit the Mediterranean climate. Comfortable shoes enhance ruin tours. Kos’ historic richness offers a vibrant Greek stop, blending archaeology with island charm.

Port Info Link Port Excursions Link

Day 3•Wednesday, Sep 24

Rhodes, Greece

Arrival: 8:00 AM•Departure: 10:00 PM

Rhodes, Greece, offers docking at Rhodes Port. Travelers explore Medieval City and Lindos Acropolis. Excursions include snorkeling at Kallithea Springs. Local markets sell souvlaki. The peak season, May to September, brings warm weather for coastal tours. Photography captures Knights’ Street and Aegean vistas. Dining onboard includes moussaka, a Greek favorite. Souvenirs, like ceramic crafts, are sold in ship shops. Briefings cover Dodecanese history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance historic walks. Rhodes’ cultural charm offers a vibrant Greek stop. Cruise travelers enjoy a mix of UNESCO landmarks and scenic beaches, making Rhodes an engaging destination for exploration.

Port Info Link Port Excursions Link

Day 4•Thursday, Sep 25

Bodrum, Turkey

Arrival: 7:00 AM•Departure: 5:00 PM

Bodrum, Turkey, docks at Bodrum Cruise Port, a 10-minute walk to the town center, population 180,000. Travelers visit the 15th-century Castle of St. Peter, housing an underwater archaeology museum. Local markets sell Turkish delight. Excursions to Ephesus, 2 hours north, explore Roman ruins. Gümüşlük Beach, 30 minutes west, offers snorkeling. Peak season May to October; taxis 20-50 TRY. Dining includes meze at seaside tavernas. Souvenirs feature evil eye charms.

Port Info Link Port Excursions Link

Day 5•Friday, Sep 26

At Sea

Arrival: 12:00 AM•Departure: 11:59 PM

Day at sea aboard the Opera — explore the ship's signature dining, entertainment, and onboard activities.

Day 6•Saturday, Sep 27

Bari, Italy

Arrival: 7:00 AM•Departure: 7:00 PM

Bari, Italy, offers docking at Bari Port. Travelers explore Basilica of San Nicola and Bari Vecchia. Excursions visit Alberobello’s trulli houses. Local markets sell orecchiette. The peak season, April to October, brings warm weather for coastal tours. Photography captures medieval alleys and Adriatic vistas. Dining onboard includes tiella, an Apulian favorite. Souvenirs, like ceramic crafts, are sold in ship shops. Briefings cover Norman history. Light clothing and sun protection suit the Mediterranean climate, while comfortable shoes enhance historic walks. Bari’s cultural charm offers a vibrant Italian stop. Cruise travelers enjoy a mix of historic landmarks and scenic coasts, making Bari an engaging destination for exploring Italy’s Apulia region.

Port Info Link Port Excursions Link

Day 7•Sunday, Sep 28

At Sea

Arrival: 12:00 AM•Departure: 11:59 PM

Day at sea aboard the Opera — explore the ship's signature dining, entertainment, and onboard activities.

Day 8•Monday, Sep 29

Piraeus (Athens), Greece

Arrival: 7:00 AM•Departure: —

Returning to Piraeus (Athens), Greece — see Day 1 above for port info.

Port Info Link Port Excursions Link

Weather Forecast

MSC Opera - September 22, 2025 Weather Forecast

Average monthly weather for your cruise ports

Piraeus (Athens), Greece

☀️

September

Typical Weather

101°F

Average High

58°F

Average Low

Rainfall

0.04in

Daily average

1.1 in monthly total

Shore Excursions

Explore the most popular excursion options at each port.

From beach breaks and snorkeling to local food tours and cultural landmarks, these shore excursions help you make the most of every stop. Browse by port below to compare top-rated options and plan your day before you board.

See all Piraeus Shore Tours

Itinerary Safety Score

Based on comprehensive research of cruise port safety information, including recent crime reports, travel advisories, Global Peace Index rankings, and specific port security concerns, we've created a "safety score" for each cruise port stop. The overall rating below represents a combined score for your specific cruise itinerary.

Itinerary Safety Rank

70 / 100

safer than 70% of all cruises

/ 10

Piraeus

Piraeus is generally safe for cruise travelers, but caution is advised at night and in crowded areas due to petty theft and potential disruptions.

/ 10

Kos

Kos is generally safe for tourists, but they should stay vigilant against petty theft in crowded areas and secure their belongings.

/ 10

Rhodes

Rhodes is generally safe for travelers, but staying vigilant in crowded areas is advised to avoid pickpocketing and minor scams.

/ 10

Bodrum

Bodrum is generally safe, but travelers should stay vigilant in crowded areas to prevent petty crimes like pickpocketing.

/ 10

Bari

Travelers should stay vigilant in Bari, securing belongings and avoiding less populated areas after dark to minimize safety risks.

Cruise Ship

⚓ Tonnage

65,591

vs avg 136,380

🛠️ Year Built

2,004

vs avg 2,013

📏 Length (ft)

902

vs avg 1,030

👥 Passenger Count

2,679

vs avg 4,494

The Opera has a construction date of 2004 and a total size of 65,591 gross tons. The ship measures 902 feet in length. MSC Opera is included in MSC’s Lirica class. At full capacity, the MSC Opera holds 2,679 passengers. That includes 1,951 cruise vacationers and 728 staff members. The Opera total number of staterooms is 1,068.

Full MSC Opera Ship Info

Click above for more MSC Opera stats, tips, imagery, and more.

📊Size comparison chart against other ships
🍸Bars, restaurants, and venue highlights
🛠️Renovation and dry-dock schedule
❓FAQ's about MSC Opera

Also of interest:

MSC Opera Deck Plans MSC Opera Cabin Search MSC Opera Health Score

Other MSC Opera Sailings

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← Previous sailing

Sep 21, 2025

7-Night 7 Night Eastern Mediterranean (Venice-Marghera Roundtrip)

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MSC Opera schedule

Full itinerary calendar

Next sailing →

Sep 26, 2025

7-Night 7 Night Eastern Mediterranean (Bari Roundtrip)

MSC Opera September 22, 2025 FAQ

What's the cheapest cabin on the MSC Opera September 22, 2025 cruise?▾

Live pricing is not currently available for this sailing. Sign up for price-drop alerts above to be notified when fares appear.

What's the weather like on the MSC Opera September 22, 2025 route?▾

Across the ports visited on this 7-night route, September averages 99°F highs and 60°F lows. See the per-port weather forecast section above for daily detail.

How safe is the September 22, 2025 MSC Opera itinerary?▾

This itinerary scores 7.0 out of 10 on the Gangwaze Itinerary Safety Score, averaged across 5 ports. We weight current travel advisories, recent crime data, and Global Peace Index signals — see the Safety Score section above for the full per-port breakdown.

When does the MSC Opera sail and return on this itinerary?▾

The MSC Opera departs Piraeus (Athens), Greece on Monday, September 22, 2025 at 8:00 PM and returns on Monday, Sep 29th, 2025 at 7:00 AM. Total duration: 7 nights.

Who is the cruise director for the MSC Opera sailing on September 22, 2025?▾

Cruise director assignment for this sail date is not currently confirmed in our records.

Can I track price drops for this MSC Opera itinerary?▾

Yes — use the price tracking opt-in on this page to get an email when cabin prices drop for this exact sailing. We snapshot fares daily.

Researched and assembled by Gangwaze Cruise Editorial using daily-refreshed itinerary, pricing, weather, and safety data.

Last Updated: May 18, 2026